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Translocase Of Outer Mitochondrial Membrane 20 (TOMM20)

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MAS20; MOM19; TOM20; Mitochondrial 20 kDa outer membrane protein; Outer mitochondrial membrane receptor Tom20

Translocase Of Outer Mitochondrial Membrane 20 (TOMM20)
CCC M365
HGNC 20947
MGI 1915202
PubMed 7498524
RGD 708467
UniProt Q15388
Wiki Tom20
The protein import machinery of the mitochondrial outer membrane is comprised of a dynamic complex of proteins that mediates translocation of cytosolic precursor proteins into or across the membrane. Several proteins within this complex have been identified, such as Mas20p in yeast and MOM19 in Neurospora crassa .
The 145-amino acid human polypeptide shares high similarity with Mas20p and MOM19 within the N-terminal region, but exhibits only weak homology to the tetratricopeptide-repeat B domain that is found in the other 2 proteins. The authors showed that human Mas20p is targeted and inserted into the outer membrane of isolated rat heart mitochondria in the N(in)-to-C(cyto) orientation.

Organism species: Homo sapiens (Human)

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Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
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Antibodies n/a Monoclonal Antibody to Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocase Of Outer Mitochondrial Membrane 20 (TOMM20) ELISA Kit Customized Service Offer
  1. "Identification of the human mitochondrial protein import receptor, huMas20p. Complementation of delta mas20 in yeast."FEBS Lett. 373:45-50(1995) [PubMed] [Europe PMC] [Abstract]
  2. "A human homolog of the mitochondrial protein import receptor Mom19 can assemble with the yeast mitochondrial receptor complex."FEBS Lett. 375:307-310(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Gene structure of the human mitochondrial outer membrane receptor tom20 and evolutionary study of its family of processed pseudogenes."Gene 239:283-291(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1."DNA Res. 1:27-35(1994) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane."Biochem. Biophys. Res. Commun. 369:958-963(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Identification and characterization of mitochondrial targeting sequence of human apurinic/apyrimidinic endonuclease 1."J. Biol. Chem. 285:14871-14881(2010) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  18. "The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy."Nature 510:370-375(2014) [PubMed] [Europe PMC] [Abstract]
  19. "USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria."Nat. Cell Biol. 17:160-169(2015) [PubMed] [Europe PMC] [Abstract]