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Transcription Factor Dp1 (TFDP1)

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DP1; DRTF1; DRTF1-polypeptide 1; E2F dimerization partner 1

Transcription Factor Dp1 (TFDP1)
CCC M355
HGNC 11749
MGI 101934
PubMed 23849371
UniProt Q14186
Wiki TFDP1
The E2F transcription factor family regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors.
The protein was isolated by virtue of its binding to a DNA sequence taken from the adenovirus E2A promoter. TFDP1 is a component of the DRTF1/E2F transcription factor complex, which coordinates events in the cell cycle by interacting with RB1, the retinoblastoma gene product, and RB-related proteins. DRTF1 activity is downregulated in differentiating embryonal carcinoma cells, and E2F activity is induced in adenovirus-infected HeLa cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM355Hu01 Recombinant Transcription Factor Dp1 (TFDP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM355Hu01 Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Transcription Factor Dp1 (TFDP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor Dp1 (TFDP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transcription Factor Dp1 (TFDP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transcription Factor Dp1 (TFDP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transcription Factor Dp1 (TFDP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transcription Factor Dp1 (TFDP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transcription Factor Dp1 (TFDP1) ELISA Kit Customized Service Offer
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