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Suppressor Of Zeste 12 Homolog (SUZ12)

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CHET9; JJAZ1; Chromatin precipitated E2F target 9 protein; Joined to JAZF1 protein

Suppressor Of Zeste 12 Homolog (SUZ12)
CCC M329
HGNC 17101
MGI 1261758
PubMed 22505317
UniProt Q15022
Wiki SUZ12
SUZ12 has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined.Suz12 mutants exhibited very strong homeotic transformations and that Suz12 function is required throughout development to maintain the repressed state of Hox genes in Drosophila. Unlike most other Polycomb group mutations, Suz12 mutations are strong suppressors of position-effect variegation, suggesting that Suz12 also functions in heterochromatin-mediated repression. Furthermore, Suz12 function is required for germ cell development. The SUZ12 protein is highly conserved in vertebrates and is also related to several Arabidopsis proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM329Hu01 Recombinant Suppressor Of Zeste 12 Homolog (SUZ12) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM329Hu21 Monoclonal Antibody to Suppressor Of Zeste 12 Homolog (SUZ12) WB; IHC; ICC; IP.
PAM329Hu01 Polyclonal Antibody to Suppressor Of Zeste 12 Homolog (SUZ12) WB; IHC; ICC; IP.
Assay Kits SEM329Hu ELISA Kit for Suppressor Of Zeste 12 Homolog (SUZ12) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Suppressor Of Zeste 12 Homolog (SUZ12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Suppressor Of Zeste 12 Homolog (SUZ12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Suppressor Of Zeste 12 Homolog (SUZ12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Suppressor Of Zeste 12 Homolog (SUZ12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Suppressor Of Zeste 12 Homolog (SUZ12) ELISA Kit Customized Service Offer
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