Sialyltransferase 8C (SIAT8C)
[Edit]ST8SIA3; ST8 Alpha N-Acetyl Neuraminide Alpha 2,8-Sialyltransferase 3; Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
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ST8SIA3 belongs to a family of sialyltransferases that form sialyl-alpha-2,8-sialyl-R linkages at the nonreducing termini of glycoconjugates.ST8SIA3 contains an N-terminal signal/membrane-anchoring domain, followed by a central sialyl L motif and a sialyl S motif.
The deduced 380-amino acid protein has a type II transmembrane topology and 3 potential N-glycosylation sites. ST8SIA3 shares 96% amino acid identity with mouse St8sia3. Northern blot analysis of adult and fetal tissues detected an 11-kb transcript mainly expressed in fetal and adult brain. A 5.5-kb transcript was also expressed in fetal liver. The pattern of human ST8SIA3 expression was distinct from that found for mouse St8sia3.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Sialyltransferase 8C (SIAT8C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Sialyltransferase 8C (SIAT8C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Sialyltransferase 8C (SIAT8C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Sialyltransferase 8C (SIAT8C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Sialyltransferase 8C (SIAT8C) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Sialyltransferase 8C (SIAT8C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Sialyltransferase 8C (SIAT8C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Sialyltransferase 8C (SIAT8C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Sialyltransferase 8C (SIAT8C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Sialyltransferase 8C (SIAT8C) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Sialyltransferase 8C (SIAT8C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Sialyltransferase 8C (SIAT8C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Sialyltransferase 8C (SIAT8C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Sialyltransferase 8C (SIAT8C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Sialyltransferase 8C (SIAT8C) | ELISA Kit Customized Service Offer |
- "Cloning and expression of cDNA for a human Sia alpha 2,3Gal beta 1,4GlcNA:alpha 2,8-sialyltransferase (hST8Sia III)."Arch. Biochem. Biophys. 360:41-46(1998) [PubMed] [Europe PMC] [Abstract]
- "Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha2,8-Sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III."J. Biol. Chem. 275:18594-18601(2000) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]