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Cytospin B (CYTSB)

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SPECC1; NSP5; HCMOGT-1; Nuclear structure protein 5; Sperm Antigen With Calponin Homology And Coiled-Coil Domains 1; Cytokinesis And Spindle Organization B

Cytospin B (CYTSB)
CCC M269
HGNC 30615
MGI 2442356
PubMed 15602574
RGD 1309718
UniProt Q5M775
Wiki SPECC1
Database analysis showed that the SPECC1 gene is almost identical to the human sperm antigen, HCMOGT1. There are 2 possible 5-prime ends and 2 possible 3-prime ends. The major coding sequence shared by all isolated transcripts encodes an ATPase domain similar to that of SMC family members and a coiled-coil domain commonly seen in motor or structure proteins.
The larger transcript was also expressed in spleen, but all other normal tissues examined showed little or no SPECC1 expression. Variable expression was detected in some human cancer cell lines, including HeLa cells. Immunohistochemical analysis of HeLa cells detected SPECC1 in the nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytospin B (CYTSB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytospin B (CYTSB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytospin B (CYTSB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytospin B (CYTSB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytospin B (CYTSB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM269Mu01 Recombinant Cytospin B (CYTSB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM269Mu01 Polyclonal Antibody to Cytospin B (CYTSB) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cytospin B (CYTSB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytospin B (CYTSB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytospin B (CYTSB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytospin B (CYTSB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytospin B (CYTSB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytospin B (CYTSB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytospin B (CYTSB) ELISA Kit Customized Service Offer
  1. "A gene highly expressed in tumor cells encodes novel structure proteins."Oncogene 23:9438-9446(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)."Cancer Res. 64:2649-2651(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]