Specificity Protein 2 (SP2)

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Sp2 Transcription Factor

Specificity Protein 2 (SP2)
SP2 encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins.
It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.SP2 cDNA encodes a 495-amino acid polypeptide which is 72% identical to SP1 within the zinc finger domain. SP2, unlike SP3, has limited homology to SP1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Specificity Protein 2 (SP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Specificity Protein 2 (SP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Specificity Protein 2 (SP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Specificity Protein 2 (SP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Specificity Protein 2 (SP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Specificity Protein 2 (SP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Specificity Protein 2 (SP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Specificity Protein 2 (SP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Specificity Protein 2 (SP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Specificity Protein 2 (SP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Specificity Protein 2 (SP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Specificity Protein 2 (SP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Specificity Protein 2 (SP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Specificity Protein 2 (SP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Specificity Protein 2 (SP2) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 1:223-229(1994) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression."Mol. Cell. Biol. 12:4251-4261(1992) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]