≡

Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2)

[Edit]

Msl1; U2 small nuclear ribonucleoprotein B''

Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2)
CCC M260
HGNC 11155
MGI 104805
PubMed 2951739
RGD 1310194
UniProt P08579
Wiki SNRPB2
SNRPB2 associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.
By screening a human cell expression library with autoimmune sera from patients with SLE or other rheumatic diseases, Habets et al. (1987) isolated a cDNA encoding SNRPB2. The predicted 225-amino acid protein has an apparent molecular mass of 26.5 kD by SDS-PAGE.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Small Nuclear Ribonucleoprotein Polypeptide B2 (SNRPB2) ELISA Kit Customized Service Offer
  1. "Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B' antigen."Proc. Natl. Acad. Sci. U.S.A. 84:2421-2425(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Crooked neck is a component of the human spliceosome and implicated in the splicing process."Biochim. Biophys. Acta 1576:287-297(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."RNA 8:426-439(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "Crystal structure of the spliceosomal U2B'-U2A' protein complex bound to a fragment of U2 small nuclear RNA."Nature 394:645-650(1998) [PubMed] [Europe PMC] [Abstract]
  10. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]