SHC SH2 Domain Binding Protein 1 (SHCBP1)

[Edit]

SHC SH2 Domain Binding Protein 1 (SHCBP1)
Shcbp1 associates with the p52 and p46 Shc isoforms. Precipitation studies indicated that association of Shcbp1 and Shc is mediated through the SH2 domain of Shc and that this interaction is independent of tyrosine phosphorylation.The deduced 668-amino acid mouse protein has a predicted molecular mass of 75 kD and contains 23 tyrosine residues, several of which are found within good consensus binding motifs for SH2 domains. Northern blot analysis of mouse tissues detected strong expression in testis and lower expression in spleen, lung, and heart. Shcbp1 mRNA expression was observed at all stages of mouse embryonic development, and both Shcbp1 mRNA and protein expression are restricted to tissues containing actively dividing cells and proliferating cells in culture.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SHC SH2 Domain Binding Protein 1 (SHCBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SHC SH2 Domain Binding Protein 1 (SHCBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SHC SH2 Domain Binding Protein 1 (SHCBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SHC SH2 Domain Binding Protein 1 (SHCBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for SHC SH2 Domain Binding Protein 1 (SHCBP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SHC SH2 Domain Binding Protein 1 (SHCBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SHC SH2 Domain Binding Protein 1 (SHCBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SHC SH2 Domain Binding Protein 1 (SHCBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SHC SH2 Domain Binding Protein 1 (SHCBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for SHC SH2 Domain Binding Protein 1 (SHCBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SHC SH2 Domain Binding Protein 1 (SHCBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SHC SH2 Domain Binding Protein 1 (SHCBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SHC SH2 Domain Binding Protein 1 (SHCBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SHC SH2 Domain Binding Protein 1 (SHCBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for SHC SH2 Domain Binding Protein 1 (SHCBP1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  11. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]