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Splicing Factor 3B Subunit 3 (SF3B3)

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RSE1; SAP130; SF3b130; STAF130; Spliceosome-associated protein 130; Pre-mRNA-splicing factor SF3b 130 kDa subunit

Splicing Factor 3B Subunit 3 (SF3B3)
CCC M216
HGNC 10770
MGI 1289341
PubMed 23359068
RGD 1311636
UniProt Q15393
Wiki SF3B3
SF3B3 encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Splicing Factor 3B Subunit 3 (SF3B3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Splicing Factor 3B Subunit 3 (SF3B3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Splicing Factor 3B Subunit 3 (SF3B3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Splicing Factor 3B Subunit 3 (SF3B3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Splicing Factor 3B Subunit 3 (SF3B3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM216Mu01 Recombinant Splicing Factor 3B Subunit 3 (SF3B3) Positive Control; Immunogen; SDS-PAGE; WB.
RPM216Mu02 Recombinant Splicing Factor 3B Subunit 3 (SF3B3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM216Mu01 Polyclonal Antibody to Splicing Factor 3B Subunit 3 (SF3B3) WB; IHC; ICC; IP.
PAM216Mu02 Polyclonal Antibody to Splicing Factor 3B Subunit 3 (SF3B3) WB; IHC; ICC; IP.
Assay Kits SEM216Mu ELISA Kit for Splicing Factor 3B Subunit 3 (SF3B3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Splicing Factor 3B Subunit 3 (SF3B3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Splicing Factor 3B Subunit 3 (SF3B3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Splicing Factor 3B Subunit 3 (SF3B3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Splicing Factor 3B Subunit 3 (SF3B3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Splicing Factor 3B Subunit 3 (SF3B3) ELISA Kit Customized Service Offer
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  9. "Molecular architecture of the multiprotein splicing factor SF3b."Science 300:980-984(2003) [PubMed] [Europe PMC] [Abstract]
  10. "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome."RNA 10:929-941(2004) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]