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Serum Deprivation Response Protein (SDPR)

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PS-p68; SDR; Cavin-2; Phosphatidylserine Binding Protein

Serum Deprivation Response Protein (SDPR)
CCC M204
HGNC 10690
MGI 99513
PubMed 18422756
RGD 1359345
UniProt O95810
Wiki SDPR
SDPR encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein has also been shown to be a substrate for protein kinase C (PKC) phosphorylation.
The SDPR cDNA encodes a deduced 425-amino acid peptide with a calculated molecular mass of 47.2 kD. The human and mouse proteins share 84% sequence identity; both contain a leucine zipper-like domain with 7 repeats and 2 putative protein kinase C phosphorylation sites. Northern blot analysis of various human tissues showed nearly ubiquitous expression of a 3.1-kb transcript, which was always coexpressed with a shorter transcript. Highest expression was detected in heart and lung.SDPR is able to bind PS liposomes in a calcium-independent manner.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serum Deprivation Response Protein (SDPR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) Polyclonal Antibody Customized Service Offer
Assay Kits SEM204Hu ELISA Kit for Serum Deprivation Response Protein (SDPR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serum Deprivation Response Protein (SDPR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serum Deprivation Response Protein (SDPR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serum Deprivation Response Protein (SDPR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serum Deprivation Response Protein (SDPR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serum Deprivation Response Protein (SDPR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serum Deprivation Response Protein (SDPR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serum Deprivation Response Protein (SDPR) ELISA Kit Customized Service Offer
  1. "The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein."Genomics 57:120-129(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].
  4. , Submitted (NOV-2005) to UniProtKB
  5. "Purification and characterization of a major phosphatidylserine-binding phosphoprotein from human platelets."Biochem. J. 269:729-734(1990) [PubMed] [Europe PMC] [Abstract]
  6. "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
  7. "MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance."Mol. Cell. Biol. 28:3424-3436(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]