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RAP1B, Member Of RAS Oncogene Family (RAP1B)

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K-REV; RAL1B; GTP-binding protein smg p21B

RAP1B, Member Of RAS Oncogene Family (RAP1B)
CCC M100
HGNC 9857
MGI 894315
PubMed 20733035
RGD 620577
UniProt P61224
Wiki RAP1B
The deduced 184-amino acid protein is 95% identical to RAP1A. RAP1B shares several properties with the RAS protein, suggesting that it may bind GTP/GDP and have a membrane location.RAP1B is mainly located at the membrane, but translocates to the cytosol upon activation. In activated platelets, RAP1B interacts with the reorganized actin-based cytoskeleton. RAP1B is activated by phosphorylation, increased intracellular Ca(2+), and by agonist-induced stimulation of Gi, which results in the rapid binding of GTP to RAP1B. RAP1B is posttranslationally modified by the geranylgeranylation of cys181. Further modifications cause proteolytic removal of the last 3 C-terminal amino acids, followed by partial methylation of the remaining terminal cysteinyl carboxyl group.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAP1B, Member Of RAS Oncogene Family (RAP1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAP1B, Member Of RAS Oncogene Family (RAP1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAP1B, Member Of RAS Oncogene Family (RAP1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAP1B, Member Of RAS Oncogene Family (RAP1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAP1B, Member Of RAS Oncogene Family (RAP1B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAP1B, Member Of RAS Oncogene Family (RAP1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAP1B, Member Of RAS Oncogene Family (RAP1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAP1B, Member Of RAS Oncogene Family (RAP1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAP1B, Member Of RAS Oncogene Family (RAP1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAP1B, Member Of RAS Oncogene Family (RAP1B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAP1B, Member Of RAS Oncogene Family (RAP1B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAP1B, Member Of RAS Oncogene Family (RAP1B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAP1B, Member Of RAS Oncogene Family (RAP1B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAP1B, Member Of RAS Oncogene Family (RAP1B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAP1B, Member Of RAS Oncogene Family (RAP1B) ELISA Kit Customized Service Offer
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