RAB3A Interacting Protein (RAB3IP)

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RABIN3; RABIN8; SSX2-interacting protein

RAB3A Interacting Protein (RAB3IP)
RAB3IP has several sites for N-glycosylation and phosphorylation. Northern blot analysis detected a 2.1-kb transcript in brain, kidney, heart, placenta, and pancreas, but not in skeletal muscle and liver. Transcripts of 3.8 and 10.2 kb were also detected in brain and kidney.
EST database analysis revealed that RAB3IP was also expressed in retina, fetal thymus, and B-cell germinal centers. In vitro transcription and translation of RAB3IP cDNA resulted in a protein that migrated at an apparent molecular mass of 56 kD by SDS-PAGE. Immunofluorescence analysis of transfected HeLa cells localized RAB32IP in the cytoplasm; however, coexpression of RAB3IP with SSX2 led to colocalization of both proteins in the nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3A Interacting Protein (RAB3IP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3A Interacting Protein (RAB3IP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3A Interacting Protein (RAB3IP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3A Interacting Protein (RAB3IP) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3A Interacting Protein (RAB3IP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3A Interacting Protein (RAB3IP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3A Interacting Protein (RAB3IP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3A Interacting Protein (RAB3IP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3A Interacting Protein (RAB3IP) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3A Interacting Protein (RAB3IP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB3A Interacting Protein (RAB3IP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB3A Interacting Protein (RAB3IP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB3A Interacting Protein (RAB3IP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB3A Interacting Protein (RAB3IP) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB3A Interacting Protein (RAB3IP) ELISA Kit Customized Service Offer
  1. "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP."Genes Chromosomes Cancer 34:285-298(2002) [PubMed] [Europe PMC] [Abstract] and Teratocarcinoma.
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] and Colon.
  4. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors."J. Cell Biol. 191:367-381(2010) [PubMed] [Europe PMC] [Abstract]
  9. "A molecular network for de novo generation of the apical surface and lumen."Nat. Cell Biol. 12:1035-1045(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]