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Processing Of Precursors 5 (POP5)

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RPP2; RPP20; Ribonuclease P/MRP protein subunit POP5

Processing Of Precursors 5 (POP5)
CCC M049
HGNC 17689
MGI 2151221
PubMed 11413139
RGD 1311819
UniProt Q969H6
Wiki POP5
POP5. The deduced 163-amino acid protein has a calculated molecular mass of 18.8 kD. Western blot analysis of HeLa cells detected endogenous POP5 at an apparent molecular mass of 19 kD.
HeLa cell POP5 associated with RNase MRP and RNase P RNAs. The immunoprecipitated RNase P complex was able to cleave pre-tRNA into mature tRNA and its 5-prime leader sequence, indicating that POP5 is part of the catalytically active RNase P complex. Mutation analysis showed that the C terminus of POP5 was not required for association with RNase MRP or RNase P complexes or for RNase P activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Processing Of Precursors 5 (POP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Processing Of Precursors 5 (POP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Processing Of Precursors 5 (POP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Processing Of Precursors 5 (POP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Processing Of Precursors 5 (POP5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Processing Of Precursors 5 (POP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Processing Of Precursors 5 (POP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Processing Of Precursors 5 (POP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Processing Of Precursors 5 (POP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Processing Of Precursors 5 (POP5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Processing Of Precursors 5 (POP5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Processing Of Precursors 5 (POP5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Processing Of Precursors 5 (POP5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Processing Of Precursors 5 (POP5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Processing Of Precursors 5 (POP5) ELISA Kit Customized Service Offer
  1. "hPop5, a protein subunit of the human RNase MRP and RNase P endoribonucleases."J. Biol. Chem. 276:31635-31641(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex."Nucleic Acids Res. 32:2138-2146(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]