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Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1)

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LL5A

Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1)
CCC M016
HGNC 23697
MGI 2143230
PubMed 20587420
RGD 620878
UniProt Q86UU1
Wiki PHLDB1
PHLDB1 contains at least 1,234 amino acids and shares a high degree of similarity with rat Ll5. RT-PCR detected PHLDB1 in all tissues examined, with highest expression in ovary, brain, lung, and kidney.The full-length 1,377-amino acid protein contains an N-terminal phosphorylation-dependent forkhead-associated (FHA) protein interaction domain, followed by a bipartite nuclear localization signal, a central chromosome segregation ATPase (SMC) domain, and a C-terminal pleckstrin (PLEK) homology (PH) domain. EST database analysis suggested that variant-1 was the major transcript.isolated C-terminal PH domain of LL5A interacted with all phosphoinositides examined, with highest affinity for phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3). It did not interact with PtdIns or with any other phospholipid examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pleckstrin Homology Like Domain Family B, Member 1 (PHLDB1) ELISA Kit Customized Service Offer
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