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PDZ And LIM Domain Protein 7 (PDLIM7)

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LMP1; LMP3; LMP4; Protein enigma; LIM mineralization protein

PDZ And LIM Domain Protein 7 (PDLIM7)
CCC M000
HGNC 22958
MGI 1914649
PubMed 19895804
RGD 628769
UniProt Q9NR12
Wiki PDLIM7
PDLIM7 is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PDZ And LIM Domain Protein 7 (PDLIM7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PDZ And LIM Domain Protein 7 (PDLIM7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PDZ And LIM Domain Protein 7 (PDLIM7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PDZ And LIM Domain Protein 7 (PDLIM7) CLIA Kit Customized Service Offer
n/a ELISA Kit for PDZ And LIM Domain Protein 7 (PDLIM7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PDZ And LIM Domain Protein 7 (PDLIM7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PDZ And LIM Domain Protein 7 (PDLIM7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PDZ And LIM Domain Protein 7 (PDLIM7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PDZ And LIM Domain Protein 7 (PDLIM7) CLIA Kit Customized Service Offer
n/a ELISA Kit for PDZ And LIM Domain Protein 7 (PDLIM7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PDZ And LIM Domain Protein 7 (PDLIM7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PDZ And LIM Domain Protein 7 (PDLIM7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PDZ And LIM Domain Protein 7 (PDLIM7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PDZ And LIM Domain Protein 7 (PDLIM7) CLIA Kit Customized Service Offer
n/a ELISA Kit for PDZ And LIM Domain Protein 7 (PDLIM7) ELISA Kit Customized Service Offer
  1. "LIM domain recognition of a tyrosine-containing tight turn."J. Biol. Chem. 269:25085-25090(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Overexpressed LIM mineralization proteins do not require LIM domains to induce bone."J. Bone Miner. Res. 17:406-414(2002) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. , Submitted (NOV-2005) to UniProtKB
  5. "Protein-protein interaction of zinc finger LIM domains with protein kinase C."J. Biol. Chem. 271:31029-31032(1996) [PubMed] [Europe PMC] [Abstract]
  6. "Shc and Enigma are both required for mitogenic signaling by Ret/ptc2."Mol. Cell. Biol. 18:2298-2308(1998) [PubMed] [Europe PMC] [Abstract]
  7. "The PDZ domain of the LIM protein enigma binds to beta-tropomyosin."Mol. Biol. Cell 10:1973-1984(1999) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin."Submitted (FEB-2009) to the PDB data bank
  14. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]