NEL Like Protein 2 (NELL2)
[Edit]NRP2; Nel-related protein 2; Protein kinase C-binding protein NELL2
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NELL2 encodes a cytoplasmic protein that contains epidermal growth factor (EGF) -like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. An alternative splice variant has been described but its full length sequence has not been determined.
NELL2 open reading frame encodes an 816-amino acid polypeptide. The amino acid sequence of NELL2 showed 80% identity to that of chicken 'nel,' and Watanabe et al. (1996) stated that NELL2 may be the actual interspecies homolog of the 'nel' gene. NELL2 was strongly expressed as a 3.6-kb transcript in human adult and fetal brain tissues.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL934Hu01 | Recombinant NEL Like Protein 2 (NELL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAL934Hu01 | Polyclonal Antibody to NEL Like Protein 2 (NELL2) | WB; IHC; ICC; IP. |
| MAL934Hu21 | Monoclonal Antibody to NEL Like Protein 2 (NELL2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEL934Hu | ELISA Kit for NEL Like Protein 2 (NELL2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant NEL Like Protein 2 (NELL2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to NEL Like Protein 2 (NELL2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to NEL Like Protein 2 (NELL2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for NEL Like Protein 2 (NELL2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for NEL Like Protein 2 (NELL2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | EPL934Ra61 | Eukaryotic NEL Like Protein 2 (NELL2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to NEL Like Protein 2 (NELL2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to NEL Like Protein 2 (NELL2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for NEL Like Protein 2 (NELL2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for NEL Like Protein 2 (NELL2) | ELISA Kit Customized Service Offer |
- "Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats."Genomics 38:273-276(1996) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]