Adaptin Ear Binding Coat Associated Protein 2 (NECAP2)

[Edit]

NECAP endocytosis-associated protein 2

Adaptin Ear Binding Coat Associated Protein 2 (NECAP2)
Through a proteomic analysis of rat brain clathrin-coated vesicles, Ritter et al. (2003) identified Necap2. The deduced 266-amino acid protein contains a WVQF motif that was shown in rat Necap1 to mediate binding to the alpha-adaptin subunit (AP2A1) of the adaptor protein-2 (AP-2) complex. Western blot analysis detected broad Necap2 expression in rat tissues.
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Adaptin Ear Binding Coat Associated Protein 2 (NECAP2) ELISA Kit Customized Service Offer
  1. "Characterization of long cDNA clones from human adult spleen."DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]