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Neuroblastoma Breakpoint Family, Member 3 (NBPF3)

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AE2; SHIIIa4; L7

Neuroblastoma Breakpoint Family, Member 3 (NBPF3)
CCC L902
HGNC 25076
PubMed 21544646
UniProt Q9H094
Wiki NBPF3
The NBPF3 gene is 633 amino acids long and contains five DUF1220 domains, which are highlighted in the image below. DUF1220 domains are found in all other members of the neuroblastoma breakpoint family. The protein has a very repetitive structure, since, along with the remaining members of its protein family, it likely arose form segmental duplications on chromosome 1.
The function of the neuroblastoma breakpoint family proteins, including NPBF3, is not yet understood by the scientific community. Because of the repetitive composition of this family of genes as well as their amplification in primates, it has been suggested that the family is involved in cognitive development and the evolution of primates.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuroblastoma Breakpoint Family, Member 3 (NBPF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuroblastoma Breakpoint Family, Member 3 (NBPF3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuroblastoma Breakpoint Family, Member 3 (NBPF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuroblastoma Breakpoint Family, Member 3 (NBPF3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Neuroblastoma Breakpoint Family, Member 3 (NBPF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Neuroblastoma Breakpoint Family, Member 3 (NBPF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Neuroblastoma Breakpoint Family, Member 3 (NBPF3) ELISA Kit Customized Service Offer
  1. "Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer."Oncogene 23:7734-7745(2004) [PubMed] [Europe PMC] [Abstract]
  2. "A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution."Mol. Biol. Evol. 22:2265-2274(2005) [PubMed] [Europe PMC] [Abstract]
  3. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]