UBX Domain Protein 11 (UBXN11)

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UBXD5; COA-1; SOC; SOCI; Socius; UBX Domain Containing Protein 5; Colorectal tumor-associated antigen COA-1

UBX Domain Protein 11 (UBXN11)
UBXD5 encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation.
It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UBX Domain Protein 11 (UBXN11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UBX Domain Protein 11 (UBXN11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UBX Domain Protein 11 (UBXN11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UBX Domain Protein 11 (UBXN11) CLIA Kit Customized Service Offer
n/a ELISA Kit for UBX Domain Protein 11 (UBXN11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UBX Domain Protein 11 (UBXN11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UBX Domain Protein 11 (UBXN11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UBX Domain Protein 11 (UBXN11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UBX Domain Protein 11 (UBXN11) CLIA Kit Customized Service Offer
n/a ELISA Kit for UBX Domain Protein 11 (UBXN11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UBX Domain Protein 11 (UBXN11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UBX Domain Protein 11 (UBXN11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UBX Domain Protein 11 (UBXN11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UBX Domain Protein 11 (UBXN11) CLIA Kit Customized Service Offer
n/a ELISA Kit for UBX Domain Protein 11 (UBXN11) ELISA Kit Customized Service Offer
  1. "Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes."Cancer Res. 63:6735-6743(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Large-scale cDNA transfection screening for genes related to cancer development and progression." Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers."Mol. Cell. Biol. 22:2952-2964(2002) [PubMed] [Europe PMC] [Abstract]