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OTU Domain Containing Protein 6B (OTUD6B)

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CGI-77, DUBA5

OTU Domain Containing Protein 6B (OTUD6B)
CCC L846
HGNC 24281
MGI 1919451
PubMed 21677750
RGD 1310024
UniProt Q8N6M0
Wiki OTUD6B
Deubiquitinating enzymes (DUBs) are capable of producing a free ubiquitin moiety from ubiquitin-fused precursors and ubiquitylated proteins in cells. DUBs possess conserved catalytic regions known as the 'cys domain' and the 'his domain.' There are 2 distinct families of DUBs: ubiquitin-specific processing proteases (UBPs, or USPs) and ubiquitin C-terminal hydrolases (UCHs). DUBA5 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Kayagaki et al. (2007) identified ovarian tumor domain (OTU)-containing protein 6B (OTUD6B) in a small interfering RNA (siRNA)-based screen for OTU deubiquitinating enzyme (DUB) family members. The 3,166-basepair mRNA contains an open reading frame (ORF) predicting a 293-amino acid protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant OTU Domain Containing Protein 6B (OTUD6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to OTU Domain Containing Protein 6B (OTUD6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to OTU Domain Containing Protein 6B (OTUD6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for OTU Domain Containing Protein 6B (OTUD6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for OTU Domain Containing Protein 6B (OTUD6B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant OTU Domain Containing Protein 6B (OTUD6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to OTU Domain Containing Protein 6B (OTUD6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to OTU Domain Containing Protein 6B (OTUD6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for OTU Domain Containing Protein 6B (OTUD6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for OTU Domain Containing Protein 6B (OTUD6B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant OTU Domain Containing Protein 6B (OTUD6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to OTU Domain Containing Protein 6B (OTUD6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to OTU Domain Containing Protein 6B (OTUD6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for OTU Domain Containing Protein 6B (OTUD6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for OTU Domain Containing Protein 6B (OTUD6B) ELISA Kit Customized Service Offer
  1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis."Cell 154:169-184(2013) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]