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Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1)

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MIZ; RAI17; Zimp10; hZIMP10; Retinoic Acid Induced 17; PIAS-like protein Zimp10

Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1)
CCC L793
HGNC 16493
MGI 3040693
PubMed 23161489
RGD 1311620
UniProt Q9ULJ6
Wiki ZMIZ1
ZMIZ1 encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia.
The deduced 1,067-amino acid protein has a calculated molecular mass of 123 kD. RAI17 contains an MSX-interacting zinc finger (MIZ) domain, a nuclear localization signal sequence, and 2 proline-rich regions. In vitro transcription and translation resulted in a protein with an apparent molecular mass of 130 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger MIZ Domain Containing Protein 1 (ZMIZ1) ELISA Kit Customized Service Offer
  1. "hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci."EMBO J. 22:6101-6114(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]