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Zinc Finger Protein 143 (ZNF143)

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SBF; STAF; pHZ-1; SPH-binding factor; Selenocysteine tRNA gene transcription-activating factor

Zinc Finger Protein 143 (ZNF143)
CCC L787
HGNC 12928
MGI 1277969
PubMed 7557990
RGD 1305662
UniProt P52747
Wiki ZNF143
Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. One abundant class of such transcriptional regulators resembles the Drosophila Kruppel segmentation gene product due to the presence of repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links. Like Staf, both ZNF76 and ZNF143 contain 7 zinc fingers and an activation domain with the mRNA and snRNA activation regions. Both proteins bound Staf-responsive elements in vitro. Chimeric ZNF76 and ZNF143 proteins activated a pol II mRNA promoter and snRNA pol II and pol III promoters in Xenopus oocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 143 (ZNF143) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 143 (ZNF143) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 143 (ZNF143) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 143 (ZNF143) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 143 (ZNF143) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 143 (ZNF143) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 143 (ZNF143) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 143 (ZNF143) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 143 (ZNF143) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 143 (ZNF143) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 143 (ZNF143) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 143 (ZNF143) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 143 (ZNF143) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 143 (ZNF143) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 143 (ZNF143) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders."Genomics 27:259-264(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning of a cDNA encoding human SPH-binding factor, a conserved protein that binds to the enhancer-like region of the U6 small nuclear RNA gene promoter."Nucleic Acids Res. 26:4846-4852(1998) [PubMed] [Europe PMC] [Abstract]
  6. "CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription."Mol. Cell. Biol. 27:8729-8738(2007) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]