≡

Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3)

[Edit]

CD20L; HTM4; CD20 antigen-like protein; Hematopoietic-specific transmembrane protein 4

Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3)
CCC L757
HGNC 7317
MGI 2158468
PubMed 23799614
RGD 1310598
UniProt Q96HJ5
Wiki MS4A3
MS4A3 encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes.
The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described.Expressed specifically in hematopoietic cells and tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Membrane Spanning 4 Domains Subfamily A, Member 3 (MS4A3) ELISA Kit Customized Service Offer
  1. "Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions."Proc. Natl. Acad. Sci. U.S.A. 91:10178-10182(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human HTm4 is a hematopoietic cell cycle regulator."J. Clin. Invest. 109:51-58(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2."J. Biol. Chem. 280:17235-17242(2005) [PubMed] [Europe PMC] [Abstract]