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Moloney Leukemia Virus 10 Homolog (MOV10)

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fSAP113; gb110; Functional Spliceosome-Associated Protein 113

Moloney Leukemia Virus 10 Homolog (MOV10)
CCC L750
HGNC 7200
MGI 97054
PubMed 22727223
UniProt Q9HCE1
Wiki MOV10
By sequencing clones obtained from a fetal brain cDNA library, Nagase et al. (2000) cloned MOV10, which they designated KIAA1631. The deduced protein contains 1,032 amino acids. RT-PCR ELISA detected moderate expression in all tissues and specific brain regions examined.
Meister et al. (2005) copurified MOV10, a putative DEAD-box helicase, with a cytoplasmic HeLa cell protein complex containing AGO2 (EIF2C2), DICER, and TNRC6B. MOV10 had an apparent molecular mass of 130 kD.Meister et al. (2005) found that epitope-tagged MOV10 coimmunoprecipitated with tagged AGO1 (EIF2C1) and tagged AGO2. MOV10 was required to mediate microRNA-guided mRNA cleavage in HeLa cell culture.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Moloney Leukemia Virus 10 Homolog (MOV10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Moloney Leukemia Virus 10 Homolog (MOV10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Moloney Leukemia Virus 10 Homolog (MOV10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Moloney Leukemia Virus 10 Homolog (MOV10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Moloney Leukemia Virus 10 Homolog (MOV10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Moloney Leukemia Virus 10 Homolog (MOV10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Moloney Leukemia Virus 10 Homolog (MOV10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Moloney Leukemia Virus 10 Homolog (MOV10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Moloney Leukemia Virus 10 Homolog (MOV10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Moloney Leukemia Virus 10 Homolog (MOV10) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of novel argonaute-associated proteins."Curr. Biol. 15:2149-2155(2005) [PubMed] [Europe PMC] [Abstract]
  7. "MicroRNA silencing through RISC recruitment of eIF6."Nature 447:823-828(2007) [PubMed] [Europe PMC] [Abstract]
  8. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Capped small RNAs and MOV10 in human hepatitis delta virus replication."Nat. Struct. Mol. Biol. 15:714-721(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  14. "APOBEC3G inhibits microRNA-mediated repression of translation by interfering with the interaction between Argonaute-2 and MOV10."J. Biol. Chem. 287:29373-29383(2012) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]