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LUC7 Like Protein (LUC7L)

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LUC7-LIKE; LUC7B1; SR+89; Putative SR protein LUC7B1; Putative RNA-binding protein Luc7-like 1

LUC7 Like Protein (LUC7L)
CCC L686
HGNC 6723
MGI 1914228
PubMed 12730694
UniProt Q9NQ29
Wiki LUC7L
LUC7L may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection.The longest deduced protein contains 371 amino acids and is homologous to the S. cerevisiae Luc7 protein. LUC7L has an N-terminal conserved region followed by a C3H zinc finger, a coiled-coil domain, a C2H2 RNA-binding zinc finger, 2 overlapping bipartite nuclear localization signals, and a C-terminal RS/RE (arginine-serine-rich and arginine-glutamate-rich) motif. Northern blot analysis revealed 2 predominant transcripts of about 3.5 and 2.5 kb in all tissues examined. Several additional transcripts of 1.4 to 1.6 kb were detected. The relative expression of the splicing isoforms varied within and between tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant LUC7 Like Protein (LUC7L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to LUC7 Like Protein (LUC7L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to LUC7 Like Protein (LUC7L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for LUC7 Like Protein (LUC7L) CLIA Kit Customized Service Offer
n/a ELISA Kit for LUC7 Like Protein (LUC7L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant LUC7 Like Protein (LUC7L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to LUC7 Like Protein (LUC7L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to LUC7 Like Protein (LUC7L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for LUC7 Like Protein (LUC7L) CLIA Kit Customized Service Offer
n/a ELISA Kit for LUC7 Like Protein (LUC7L) ELISA Kit Customized Service Offer
  1. "Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain."Genomics 71:307-314(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]