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La Ribonucleoprotein Domain Family, Member 1 (LARP1)

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LARP; La Related Protein 1

La Ribonucleoprotein Domain Family, Member 1 (LARP1)
CCC L664
HGNC 29531
MGI 1890165
PubMed 20430826
RGD 1306683
UniProt Q6PKG0
Wiki LARP1
All LARP proteins, including human LARP, contain 2 conserved regions. The first conserved region shares homology with La proteins (called the La motif) whereas the second conserved region is restricted to LARP proteins. Mouse Larp1 is expressed in dorsal root ganglia and spinal cord, as well as in developing organs characterized by epithelial-mesenchymal interactions. LARP-1 appears to bind mRNA in vitro via both the La motif and the LARP1 domain. LARP-1 also appears to down-regulate the Ras-MAPK pathway. LARP-1 protein colocalizes with P bodies, which function in RNA degradation. LARP-1 functions in P-bodies to attenuate the abundance of conserved Ras-MAPK mRNAs. The cluster of LARP-1 homologs may function to control the expression of key developmental regulators.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant La Ribonucleoprotein Domain Family, Member 1 (LARP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to La Ribonucleoprotein Domain Family, Member 1 (LARP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to La Ribonucleoprotein Domain Family, Member 1 (LARP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for La Ribonucleoprotein Domain Family, Member 1 (LARP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for La Ribonucleoprotein Domain Family, Member 1 (LARP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant La Ribonucleoprotein Domain Family, Member 1 (LARP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to La Ribonucleoprotein Domain Family, Member 1 (LARP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to La Ribonucleoprotein Domain Family, Member 1 (LARP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for La Ribonucleoprotein Domain Family, Member 1 (LARP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for La Ribonucleoprotein Domain Family, Member 1 (LARP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant La Ribonucleoprotein Domain Family, Member 1 (LARP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to La Ribonucleoprotein Domain Family, Member 1 (LARP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to La Ribonucleoprotein Domain Family, Member 1 (LARP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for La Ribonucleoprotein Domain Family, Member 1 (LARP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for La Ribonucleoprotein Domain Family, Member 1 (LARP1) ELISA Kit Customized Service Offer
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