Hermansky Pudlak Syndrome Protein 3 (HPS3)

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Hermansky Pudlak Syndrome Protein 3 (HPS3)
HPS3 encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes.
The HPS3 protein contains a potential clathrin-binding motif at residues 172 to 176, 2 consensus dileucine signals, and 12 tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. Northern blot analysis demonstrated a 4.4-kb message in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Expression was greatest in kidney, with strong bands in liver and placenta.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hermansky Pudlak Syndrome Protein 3 (HPS3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hermansky Pudlak Syndrome Protein 3 (HPS3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hermansky Pudlak Syndrome Protein 3 (HPS3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hermansky Pudlak Syndrome Protein 3 (HPS3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hermansky Pudlak Syndrome Protein 3 (HPS3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hermansky Pudlak Syndrome Protein 3 (HPS3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hermansky Pudlak Syndrome Protein 3 (HPS3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hermansky Pudlak Syndrome Protein 3 (HPS3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hermansky Pudlak Syndrome Protein 3 (HPS3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hermansky Pudlak Syndrome Protein 3 (HPS3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hermansky Pudlak Syndrome Protein 3 (HPS3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hermansky Pudlak Syndrome Protein 3 (HPS3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hermansky Pudlak Syndrome Protein 3 (HPS3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hermansky Pudlak Syndrome Protein 3 (HPS3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hermansky Pudlak Syndrome Protein 3 (HPS3) ELISA Kit Customized Service Offer
  1. "Mutation of a new gene causes a unique form of Hermansky-Pudlak syndrome in a genetic isolate of central Puerto Rico."Nat. Genet. 28:376-380(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Hermansky-Pudlak syndrome type 3 in Ashkenazi Jews and other non-Puerto Rican patients with hypopigmentation and platelet storage-pool deficiency."Am. J. Hum. Genet. 69:1022-1032(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]