Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1)

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30ST3A1; 3OST3A1

Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1)
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities.
HS3ST3A1 is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heparan Sulfate-3-O-Sulfotransferase 3A1 (HS3ST3A1) ELISA Kit Customized Service Offer
  1. "Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cDNAs and identification of distinct genomic loci."J. Biol. Chem. 274:5170-5184(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry."Cell 99:13-22(1999) [PubMed] [Europe PMC] [Abstract]
  6. "Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities."J. Biol. Chem. 274:5185-5192(1999) [PubMed] [Europe PMC] [Abstract]
  7. "Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3A sulfates N-unsubstituted glucosamine residues."J. Biol. Chem. 274:38155-38162(1999) [PubMed] [Europe PMC] [Abstract]
  8. "Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1."J. Biol. Chem. 279:45185-45193(2004) [PubMed] [Europe PMC] [Abstract]