Helicase, Lymphoid Specific (HELLS)

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LSH; PASG; SMARCA6; SWI/SNF2-Related,Matrix-Associated; Actin-Dependent Regulator Of Chromatin,Subfamily A,Member 6; Proliferation-Associated SNF2-Like Protein

Helicase, Lymphoid Specific (HELLS)
HELLS encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
DNA helicases play a role in a number of processes involving DNA strand separation, including replication, repair, recombination, and transcription. human HELLS is expressed in testis and thymus, 2 tissues that are highly active in DNA recombination.the mouse Hells gene contains at least 18 exons and spans more than 26.6 kb.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Helicase, Lymphoid Specific (HELLS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Helicase, Lymphoid Specific (HELLS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Helicase, Lymphoid Specific (HELLS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Helicase, Lymphoid Specific (HELLS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Helicase, Lymphoid Specific (HELLS) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Helicase, Lymphoid Specific (HELLS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Helicase, Lymphoid Specific (HELLS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Helicase, Lymphoid Specific (HELLS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Helicase, Lymphoid Specific (HELLS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Helicase, Lymphoid Specific (HELLS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Helicase, Lymphoid Specific (HELLS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Helicase, Lymphoid Specific (HELLS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Helicase, Lymphoid Specific (HELLS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Helicase, Lymphoid Specific (HELLS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Helicase, Lymphoid Specific (HELLS) ELISA Kit Customized Service Offer
  1. "Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia."Cancer Res. 60:3612-3622(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer."Int. J. Cancer 112:8-13(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
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  7. "Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma."Cancer Lett. 197:63-68(2003) [PubMed] [Europe PMC] [Abstract]