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G2 And S-Phase Expressed Protein 1 (GTSE1)

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B99

G2 And S-Phase Expressed Protein 1 (GTSE1)
CCC L574
HGNC 13698
MGI 1352755
PubMed 23236459
RGD 1563164
UniProt Q9NYZ3
Wiki GTSE1
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
The deduced 720-amino acid protein shares 65% sequence identity with mouse Gtse1. Western blot analysis of transiently transfected COS-7 cells revealed an apparent molecular mass of about 110 kD. Transient transfection of osteosarcoma cells resulted in immunofluorescent localization of GTSE1 to microtubules and colocalization with tubulin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G2 And S-Phase Expressed Protein 1 (GTSE1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G2 And S-Phase Expressed Protein 1 (GTSE1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G2 And S-Phase Expressed Protein 1 (GTSE1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G2 And S-Phase Expressed Protein 1 (GTSE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for G2 And S-Phase Expressed Protein 1 (GTSE1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G2 And S-Phase Expressed Protein 1 (GTSE1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G2 And S-Phase Expressed Protein 1 (GTSE1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G2 And S-Phase Expressed Protein 1 (GTSE1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G2 And S-Phase Expressed Protein 1 (GTSE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for G2 And S-Phase Expressed Protein 1 (GTSE1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G2 And S-Phase Expressed Protein 1 (GTSE1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G2 And S-Phase Expressed Protein 1 (GTSE1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G2 And S-Phase Expressed Protein 1 (GTSE1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G2 And S-Phase Expressed Protein 1 (GTSE1) CLIA Kit Customized Service Offer
n/a ELISA Kit for G2 And S-Phase Expressed Protein 1 (GTSE1) ELISA Kit Customized Service Offer
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  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]