The deduced protein contains 1,095 amino acids. RT-PCR ELISA detected intermediate expression in all adult and fetal tissues and specific brain regions examined.
The full-length transcript encodes a deduced 2,241-amino acid protein with a C-terminal SANT DNA-binding domain. The other transcript is truncated in intron 21 and encodes a 1,529-amino acid protein that lacks the SANT domain. Both proteins contain several evolutionarily conserved motifs. Gon4, the C. elegans ortholog of GON4L, is a cell lineage regulator of gonadogenesis. GON4L is a transcription factor that may function in cell cycle control. Northern blot analysis detected variable expression of 7.7- and 4.8-kb GON4L transcripts in all tissues examined.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GON4 Like Protein (GON4L) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GON4 Like Protein (GON4L) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GON4 Like Protein (GON4L) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GON4 Like Protein (GON4L) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GON4 Like Protein (GON4L) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GON4 Like Protein (GON4L) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GON4 Like Protein (GON4L) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GON4 Like Protein (GON4L) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GON4 Like Protein (GON4L) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GON4 Like Protein (GON4L) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GON4 Like Protein (GON4L) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GON4 Like Protein (GON4L) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GON4 Like Protein (GON4L) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GON4 Like Protein (GON4L) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GON4 Like Protein (GON4L) | ELISA Kit Customized Service Offer |
- "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
- "Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."Proteomics 7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]