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Drebrin Like Protein (DBNL)

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ABP1; HIP-55; SH3P7; CMAP; Cervical mucin-associated protein; Drebrin-F; HPK1-interacting protein of 55 kDa; SH3 domain-containing protein 7

Drebrin Like Protein (DBNL)
CCC L448
HGNC 2696
MGI 700006
PubMed 23283305
RGD 70941
UniProt Q9UJU6
Wiki DBNL
The predicted 430-amino acid protein has a calculated molecular mass of 48 kD. The N terminus of HIP55 contains a putative actin-binding domain found in drebrins, which are involved in brain development, and the C terminus contains an SH3 domain. Western blot analysis detected a 55-kD protein. Northern blot analysis revealed ubiquitous expression of a 2.3-kb transcript, with highest levels in spleen and peripheral blood leukocytes.
HIP55 did not contribute to early formation of T cell-antigen-presenting cell (APC) conjugates. However, they identified HIP55 as a key constituent of the immunologic synapse, regulating T-cell activation by bridging T-cell receptors and the actin cytoskeleton to gene activation and endocytic processes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Drebrin Like Protein (DBNL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Drebrin Like Protein (DBNL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Drebrin Like Protein (DBNL) Polyclonal Antibody Customized Service Offer
Assay Kits SEL448Hu ELISA Kit for Drebrin Like Protein (DBNL) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Drebrin Like Protein (DBNL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Drebrin Like Protein (DBNL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Drebrin Like Protein (DBNL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Drebrin Like Protein (DBNL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Drebrin Like Protein (DBNL) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Drebrin Like Protein (DBNL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Drebrin Like Protein (DBNL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Drebrin Like Protein (DBNL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Drebrin Like Protein (DBNL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Drebrin Like Protein (DBNL) ELISA Kit Customized Service Offer
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  19. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  20. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  21. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  22. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  23. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  24. "NMR solution structures of actin depolymerizing factor homology domains."Protein Sci. 18:2384-2392(2009) [PubMed] [Europe PMC] [Abstract]