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DEAH Box Polypeptide 16 (DHX16)

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DBP2; DDX16; PRP8; PRPF2; DEAH(Asp-Glu-Ala-His)Box Polypeptide 16; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

DEAH Box Polypeptide 16 (DHX16)
CCC L433
HGNC 2739
MGI 1916442
PubMed 22365833
RGD 1302963
UniProt O60231
Wiki DHX16
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
DHX16 encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DEAH Box Polypeptide 16 (DHX16) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DEAH Box Polypeptide 16 (DHX16) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DEAH Box Polypeptide 16 (DHX16) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DEAH Box Polypeptide 16 (DHX16) CLIA Kit Customized Service Offer
n/a ELISA Kit for DEAH Box Polypeptide 16 (DHX16) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DEAH Box Polypeptide 16 (DHX16) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DEAH Box Polypeptide 16 (DHX16) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DEAH Box Polypeptide 16 (DHX16) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DEAH Box Polypeptide 16 (DHX16) CLIA Kit Customized Service Offer
n/a ELISA Kit for DEAH Box Polypeptide 16 (DHX16) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DEAH Box Polypeptide 16 (DHX16) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DEAH Box Polypeptide 16 (DHX16) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DEAH Box Polypeptide 16 (DHX16) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DEAH Box Polypeptide 16 (DHX16) CLIA Kit Customized Service Offer
n/a ELISA Kit for DEAH Box Polypeptide 16 (DHX16) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a human DEAH-box RNA helicase, a functional homolog of fission yeast Cdc28/Prp8."Nucleic Acids Res. 26:2063-2068(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]