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Dihydroxyacetone Kinase 2 (DAK)

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NET45; DHAK; Glycerone kinase; Triokinase; ATP-dependent dihydroxyacetone kinase; Bifunctional ATP-Dependent Dihydroxyacetone Kinase/FAD-AMP Lyase(Cyclizing)

Dihydroxyacetone Kinase 2 (DAK)
CCC L405
HGNC 24552
MGI 2385084
PubMed 17600090
RGD 1311026
UniProt Q3LXA3
Wiki DAK
DAK is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclic FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined. An enzyme catalyzing the phosphorylation of dibydroxyacetone has been identified in the halophilic alga, Dunaliella parva. Since glycerol and glyceraldehyde are not substrates, the enzyme is referred to as dibydroxyacetone kinase. Dihydroxyacetone kinase was prified 9-fold by ammonium salfate fractionation foilowed by DEAE-ceilulose chromatography.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dihydroxyacetone Kinase 2 (DAK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dihydroxyacetone Kinase 2 (DAK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dihydroxyacetone Kinase 2 (DAK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dihydroxyacetone Kinase 2 (DAK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydroxyacetone Kinase 2 (DAK) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dihydroxyacetone Kinase 2 (DAK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dihydroxyacetone Kinase 2 (DAK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dihydroxyacetone Kinase 2 (DAK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dihydroxyacetone Kinase 2 (DAK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydroxyacetone Kinase 2 (DAK) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dihydroxyacetone Kinase 2 (DAK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dihydroxyacetone Kinase 2 (DAK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dihydroxyacetone Kinase 2 (DAK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dihydroxyacetone Kinase 2 (DAK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydroxyacetone Kinase 2 (DAK) ELISA Kit Customized Service Offer
  1. "Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases."Biochem. Biophys. Res. Commun. 338:1682-1689(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Dihydroxyacetone metabolism by human erythrocytes: demonstration of triokinase activity and its characterization."Blood 41:559-568(1973) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]