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COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5)

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CSN5; JAB1; MOV-34; SGN5; Signalosome subunit 5; Jun activation domain-binding protein 1

COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5)
CCC L370
HGNC 2240
MGI 1349415
RGD 1310301
UniProt Q92905
COPS5 or Csn5, is a gene conserved from humans to Saccharomyces cerevisiae. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome.
COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be a coactivator that increases the specificity of JUN/AP1 transcription factors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) CLIA Kit Customized Service Offer
n/a ELISA Kit for COP9 Constitutive Photomorphogenic Homolog Subunit 5 (COPS5) ELISA Kit Customized Service Offer
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