C-Type Lectin Domain Family 4, Member A (CLEC4A)
[Edit]CLECSF6; DCIR; DDB27; HDCGC13P; LLIR; C-type lectin DDB27; C-type lectin superfamily member 6; Dendritic cell immunoreceptor; Lectin-like immunoreceptor
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CLEC4A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.Expressed in dendritic cells, myeloid cells, B-cells and HL-60 cells (at protein level).
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL352Hu01 | Recombinant C-Type Lectin Domain Family 4, Member A (CLEC4A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to C-Type Lectin Domain Family 4, Member A (CLEC4A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to C-Type Lectin Domain Family 4, Member A (CLEC4A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEL352Hu | ELISA Kit for C-Type Lectin Domain Family 4, Member A (CLEC4A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant C-Type Lectin Domain Family 4, Member A (CLEC4A) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to C-Type Lectin Domain Family 4, Member A (CLEC4A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to C-Type Lectin Domain Family 4, Member A (CLEC4A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for C-Type Lectin Domain Family 4, Member A (CLEC4A) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for C-Type Lectin Domain Family 4, Member A (CLEC4A) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant C-Type Lectin Domain Family 4, Member A (CLEC4A) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to C-Type Lectin Domain Family 4, Member A (CLEC4A) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to C-Type Lectin Domain Family 4, Member A (CLEC4A) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for C-Type Lectin Domain Family 4, Member A (CLEC4A) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for C-Type Lectin Domain Family 4, Member A (CLEC4A) | ELISA Kit Customized Service Offer |
- "APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif."J. Immunol. 163:1973-1983(1999) [PubMed] [Europe PMC] [Abstract]
- "Cloning and characterization of a novel ITIM containing lectin-like immunoreceptor LLIR and its two transmembrane region deletion variants."Biochem. Biophys. Res. Commun. 281:131-140(2001) [PubMed] [Europe PMC] [Abstract]
- "The expression pattern of the ITIM-bearing lectin CLECSF6 in neutrophils suggests a key role in the control of inflammation."J. Leukoc. Biol. 71:871-880(2002) [PubMed] [Europe PMC] [Abstract]
- "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]