Centrosomal Protein 120kDa (CEP120)

[Edit]

CCDC100; Coiled-Coil Domain-Containing Protein 100

Centrosomal Protein 120kDa (CEP120)
CEP120 encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects.
Cep120 and Taccs regulated the integrity of microtubules coupling the centrosome and the nucleus. Cep120 interacted with Taccs and regulated the localization of Tacc3 to the centrosome. Both Cep120 and Taccs were essential for maintaining the neural progenitor pool during mouse neocortical development.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centrosomal Protein 120kDa (CEP120) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centrosomal Protein 120kDa (CEP120) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrosomal Protein 120kDa (CEP120) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrosomal Protein 120kDa (CEP120) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrosomal Protein 120kDa (CEP120) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centrosomal Protein 120kDa (CEP120) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centrosomal Protein 120kDa (CEP120) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrosomal Protein 120kDa (CEP120) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrosomal Protein 120kDa (CEP120) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrosomal Protein 120kDa (CEP120) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centrosomal Protein 120kDa (CEP120) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centrosomal Protein 120kDa (CEP120) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrosomal Protein 120kDa (CEP120) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrosomal Protein 120kDa (CEP120) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrosomal Protein 120kDa (CEP120) ELISA Kit Customized Service Offer
  1. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]