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Chaperonin Containing TCP1, Subunit 4 (CCT4)

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Cctd; SRB; T-Complex Protein 1 Subunit Delta; Stimulator of TAR RNA-binding

Chaperonin Containing TCP1, Subunit 4 (CCT4)
CCC L294
HGNC 1617
MGI 104689
PubMed 23612981
RGD 727937
UniProt P50991
Wiki CCT4
The chaperonin containing TCP1 complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin and tubulin, as well as alpha-transducin.
The deduced 539-amino acid CCT4 protein shares homology with a number of chaperonin family proteins. Northern blot analysis detected a 2.0-kb CCT4 transcript in all tissues tested. Western blot analysis showed that CCT4 is expressed as a 62-kD protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chaperonin Containing TCP1, Subunit 4 (CCT4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 4 (CCT4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 4 (CCT4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chaperonin Containing TCP1, Subunit 4 (CCT4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chaperonin Containing TCP1, Subunit 4 (CCT4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chaperonin Containing TCP1, Subunit 4 (CCT4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 4 (CCT4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 4 (CCT4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chaperonin Containing TCP1, Subunit 4 (CCT4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chaperonin Containing TCP1, Subunit 4 (CCT4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chaperonin Containing TCP1, Subunit 4 (CCT4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 4 (CCT4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 4 (CCT4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chaperonin Containing TCP1, Subunit 4 (CCT4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chaperonin Containing TCP1, Subunit 4 (CCT4) ELISA Kit Customized Service Offer
  1. "Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA."J. Biol. Chem. 271:4201-4208(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT."Mol. Cell. Biol. 18:7584-7589(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]