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Chaperonin Containing TCP1, Subunit 3 (CCT3)

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CCT-gamma; CCTG; PIG48; TCP-1-gamma; TRIC5; T-Complex Protein 1 Subunit Gamma

Chaperonin Containing TCP1, Subunit 3 (CCT3)
CCC L293
HGNC 1616
MGI 104708
PubMed 23112166
RGD 735038
UniProt P49368
Wiki CCT3
CCT3 encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
The 1.9-kb cDNA encodes a predicted 544-amino acid protein that is 98% similar to the mouse sequence and 75% similar to the yeast gene. The mRNA is expressed in a variety of human tissues and at high levels in mouse testis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chaperonin Containing TCP1, Subunit 3 (CCT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 3 (CCT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 3 (CCT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chaperonin Containing TCP1, Subunit 3 (CCT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chaperonin Containing TCP1, Subunit 3 (CCT3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chaperonin Containing TCP1, Subunit 3 (CCT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 3 (CCT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 3 (CCT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chaperonin Containing TCP1, Subunit 3 (CCT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chaperonin Containing TCP1, Subunit 3 (CCT3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chaperonin Containing TCP1, Subunit 3 (CCT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 3 (CCT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 3 (CCT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chaperonin Containing TCP1, Subunit 3 (CCT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chaperonin Containing TCP1, Subunit 3 (CCT3) ELISA Kit Customized Service Offer
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  5. , Submitted (JUL-2007) to UniProtKB
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  7. , Submitted (MAR-2007) to UniProtKB
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  9. "A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death."J. Biol. Chem. 278:51901-51910(2003) [PubMed] [Europe PMC] [Abstract]
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  13. "BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly."Proc. Natl. Acad. Sci. U.S.A. 107:1488-1493(2010) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]