Chaperonin Containing TCP1, Subunit 2 (CCT2)
[Edit]CCT-beta; CCTB; TCP-1-beta; T-Complex Protein 1 Subunit Beta
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CCT2 is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.Cyclin E (CCNE1), a partner of the cyclin-dependent kinase CDK2, is implicated in the positive control of the G1/S phase transition. CCNE1 degradation is regulated by ubiquitination and proteasomal action, which occur upon autophosphorylation and activation of the CCNE1-CDK2 complex.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL292Hu01 | Recombinant Chaperonin Containing TCP1, Subunit 2 (CCT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAL292Hu21 | Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB; IHC; ICC; IP. |
| PAL292Hu01 | Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB,IHC | |
| MAL292Hu24 | Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB; IHC; ICC; IP. | |
| MAL292Hu23 | Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB; IHC; ICC; IP. | |
| MAL292Hu22 | Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB; IHC; ICC; IP. | |
| MAL292Hu25 | Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB | |
| Assay Kits | SEL292Hu | ELISA Kit for Chaperonin Containing TCP1, Subunit 2 (CCT2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL292Mu01 | Recombinant Chaperonin Containing TCP1, Subunit 2 (CCT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPL292Mu02 | Recombinant Chaperonin Containing TCP1, Subunit 2 (CCT2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAL292Mu01 | Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB; IHC; ICC; IP. |
| PAL292Mu02 | Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | WB; IHC; ICC; IP. | |
| Assay Kits | SEL292Mu | ELISA Kit for Chaperonin Containing TCP1, Subunit 2 (CCT2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Chaperonin Containing TCP1, Subunit 2 (CCT2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Chaperonin Containing TCP1, Subunit 2 (CCT2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Chaperonin Containing TCP1, Subunit 2 (CCT2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Chaperonin Containing TCP1, Subunit 2 (CCT2) | ELISA Kit Customized Service Offer |
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- "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]