Bardet Biedl Syndrome Protein 9 (BBS9)

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B1; D1; PTHB1; C18; Parathyroid Hormone Responsive B1 Gene

Bardet Biedl Syndrome Protein 9 (BBS9)
The expression of the Bardet-Biedl syndrome 9 protein is downregulated by parathyroid hormone in osteoblastic cells, and therefore, is thought to be involved in parathyroid hormone action in bones.the B1 gene contains 24 exons and spans more than 700 kb. Exon 23 is part of a mammalian apparent long-terminal repeat retrotransposon.
The deduced 802-amino acid protein is encoded by a 3.5-kb clone and shows characteristics of a globular intracellular protein. Northern blot analysis using sequence-specific probes detected multiple transcripts of 1.2 to 4.4 kb expressed in the SaoS-2/B10 cell line and several normal tissues. Expression was detected in adult heart, skeletal muscle, lung, liver, kidney, placenta, and brain, and in fetal kidney, lung, liver, and brain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bardet Biedl Syndrome Protein 9 (BBS9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bardet Biedl Syndrome Protein 9 (BBS9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bardet Biedl Syndrome Protein 9 (BBS9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bardet Biedl Syndrome Protein 9 (BBS9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bardet Biedl Syndrome Protein 9 (BBS9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bardet Biedl Syndrome Protein 9 (BBS9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bardet Biedl Syndrome Protein 9 (BBS9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bardet Biedl Syndrome Protein 9 (BBS9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bardet Biedl Syndrome Protein 9 (BBS9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bardet Biedl Syndrome Protein 9 (BBS9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bardet Biedl Syndrome Protein 9 (BBS9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bardet Biedl Syndrome Protein 9 (BBS9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bardet Biedl Syndrome Protein 9 (BBS9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bardet Biedl Syndrome Protein 9 (BBS9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bardet Biedl Syndrome Protein 9 (BBS9) ELISA Kit Customized Service Offer
  1. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of a novel parathyroid hormone-responsive gene in human osteoblastic cells."Bone 24:305-313(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The parathyroid hormone-responsive B1 gene is interrupted by a t(1;7)(q42;p15) breakpoint associated with Wilms' tumour."Oncogene 22:1371-1380(2003) [PubMed] [Europe PMC] [Abstract]
  5. "A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis."Cell 129:1201-1213(2007) [PubMed] [Europe PMC] [Abstract]
  6. "A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened."PLoS Genet. 7:E1002358-E1002358(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene."Am. J. Hum. Genet. 77:1021-1033(2005) [PubMed] [Europe PMC] [Abstract]
  8. "BBS genotype-phenotype assessment of a multiethnic patient cohort calls for a revision of the disease definition." Hum. Mutat. 32:610-619(2011) [PubMed] [Europe PMC] [Abstract]