≡

Beta-1,3-Galactosyltransferase 3 (b3GALT3)

[Edit]

B3GALNT1; P1; GLCT3; GLOB; Beta-1,3-N-Acetylgalactosaminyltransferase 1; Globoside synthase; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase

Beta-1,3-Galactosyltransferase 3 (b3GALT3)
CCC L232
HGNC 918
MGI 1349405
PubMed 16130451
RGD 1304797
UniProt O75752
b3GALT3 is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Beta-1,3-Galactosyltransferase 3 (b3GALT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Beta-1,3-Galactosyltransferase 3 (b3GALT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Beta-1,3-Galactosyltransferase 3 (b3GALT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Beta-1,3-Galactosyltransferase 3 (b3GALT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Beta-1,3-Galactosyltransferase 3 (b3GALT3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Beta-1,3-Galactosyltransferase 3 (b3GALT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Beta-1,3-Galactosyltransferase 3 (b3GALT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Beta-1,3-Galactosyltransferase 3 (b3GALT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Beta-1,3-Galactosyltransferase 3 (b3GALT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Beta-1,3-Galactosyltransferase 3 (b3GALT3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Beta-1,3-Galactosyltransferase 3 (b3GALT3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Beta-1,3-Galactosyltransferase 3 (b3GALT3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Beta-1,3-Galactosyltransferase 3 (b3GALT3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Beta-1,3-Galactosyltransferase 3 (b3GALT3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Beta-1,3-Galactosyltransferase 3 (b3GALT3) ELISA Kit Customized Service Offer
  1. "A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family."J. Biol. Chem. 273:12770-12778(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Expression cloning of human globoside synthase cDNAs. Identification of beta3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase."J. Biol. Chem. 275:40498-40503(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular basis of the globoside-deficient P(k) blood group phenotype. Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase gene."J. Biol. Chem. 277:29455-29459(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].