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Autophagy Related Protein 7 (ATG7)

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APG7L; GSA7; Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Ubiquitin-activating enzyme E1-like protein

Autophagy Related Protein 7 (ATG7)
CCC L222
HGNC 16935
MGI 1921494
PubMed 21617129
RGD 1304817
UniProt O95352
Wiki ATG7
ATG7 was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vaculuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
The deduced 703-amino acid protein contains a central putative E1-like ATP-binding site (GxGxxG), conserved charged amino acids flanking the GxGxxG motif, and a putative E1 active site with a conserved catalytic cysteine. APG7L shares similarity with the E1 enzymes UBA2 and UBA3 (UBE1C), and it shares 38% identity with yeast Apg7. EST database analysis indicated that APG7L is expressed by many diverse tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL222Hu01 Recombinant Autophagy Related Protein 7 (ATG7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAL222Hu21 Monoclonal Antibody to Autophagy Related Protein 7 (ATG7) WB; IHC; ICC; IP.
PAL222Hu01 Polyclonal Antibody to Autophagy Related Protein 7 (ATG7) WB; IHC; ICC; IP.
Assay Kits SEL222Hu ELISA Kit for Autophagy Related Protein 7 (ATG7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL222Mu01 Recombinant Autophagy Related Protein 7 (ATG7) Positive Control; Immunogen; SDS-PAGE; WB.
RPL222Mu02 Recombinant Autophagy Related Protein 7 (ATG7) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL222Mu01 Polyclonal Antibody to Autophagy Related Protein 7 (ATG7) WB; IHC; ICC; IP.
PAL222Mu02 Polyclonal Antibody to Autophagy Related Protein 7 (ATG7) WB; IHC; ICC; IP.
Assay Kits SEL222Mu ELISA Kit for Autophagy Related Protein 7 (ATG7) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 7 (ATG7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 7 (ATG7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 7 (ATG7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Autophagy Related Protein 7 (ATG7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Autophagy Related Protein 7 (ATG7) ELISA Kit Customized Service Offer
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  18. "Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)."J. Biol. Chem. 288:9165-9176(2013) [PubMed] [Europe PMC] [Abstract]
  19. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]