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Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1)

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Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1)
CCC L213
HGNC 16011
MGI 1929735
PubMed 23405321
RGD 1310760
UniProt Q9Y576
Wiki ASB1
ASB1 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.
Sequence analysis predicted that the 335-amino acid protein, which is 94% identical to the mouse protein, contains 6 ankyrin repeats and a C-terminal SOCS box. Northern blot analysis of mouse tissues revealed wide expression of a 5.5-kb transcript, with highest expression in testis, spleen, and bone marrow.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ankyrin Repeat And SOCS Box Containing Protein 1 (ASB1) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4."Gene 258:31-41(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."DNA Res. 6:329-336(1999) [PubMed] [Europe PMC] [Abstract]
  5. "ASB proteins interact with cullin5 and Rbx2 to form E3 ubiquitin ligase complexes."FEBS Lett. 579:6796-6802(2005) [PubMed] [Europe PMC] [Abstract]