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Cellular Nucleic Acid Binding Protein (CNBP)

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CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9; CCHC-Type Zinc Finger,Nucleic Acid Binding Protein; Zinc Finger Protein 9

Cellular Nucleic Acid Binding Protein (CNBP)
CCC L110
HGNC 13164
MGI 88431
PubMed 23774591
RGD 621807
UniProt P62633
Wiki CNBP
The ZNF9 protein contains 7 zinc finger domains and is believed to function as an RNA-binding protein. A CCTG expansion in intron 1 of the ZNF9 gene results in myotonic dystrophy type 2.
Cholesterol homeostasis is maintained in part by negative feedback regulation of the genes for proteins involved in cholesterol synthesis and the cellular uptake of cholesterol. The apparent coordinate regulation of several such genes, including HMG-CoA reductase, HMG-CoA synthase, farnesylpyrophosphate synthetase, and the LDL receptor suggest that these genes may be regulated by a common trans-acting factor that is able to 'sense' the levels of cellular sterols. In common with the viral NBPs, CNBP appeared to have a strong preference for single-stranded DNA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cellular Nucleic Acid Binding Protein (CNBP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cellular Nucleic Acid Binding Protein (CNBP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cellular Nucleic Acid Binding Protein (CNBP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cellular Nucleic Acid Binding Protein (CNBP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cellular Nucleic Acid Binding Protein (CNBP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cellular Nucleic Acid Binding Protein (CNBP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cellular Nucleic Acid Binding Protein (CNBP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cellular Nucleic Acid Binding Protein (CNBP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cellular Nucleic Acid Binding Protein (CNBP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cellular Nucleic Acid Binding Protein (CNBP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cellular Nucleic Acid Binding Protein (CNBP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cellular Nucleic Acid Binding Protein (CNBP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cellular Nucleic Acid Binding Protein (CNBP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cellular Nucleic Acid Binding Protein (CNBP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cellular Nucleic Acid Binding Protein (CNBP) ELISA Kit Customized Service Offer
  1. "Identification of a zinc finger protein that binds to the sterol regulatory element."Science 245:640-643(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Organization of the gene encoding cellular nucleic acid-binding protein."Gene 163:279-282(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9."Science 293:864-867(2001) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  9. "Arginine methylation of the cellular nucleic acid binding protein does not affect its subcellular localization but impedes RNA binding."FEBS Lett. 588:1542-1548(2014) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]