Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3)
[Edit]SCA13; KSHIIID; Kv3.3; Spinocerebellar Ataxia 13; Voltage-gated potassium channel subunit Kv3.3
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The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. KCNC3 belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes.
In the mouse the gene encodes a protein of 679 amino acids. Unlike the vertebrate Shaker-related genes that have intronless coding regions, mouse Kv3.3 is encoded by at least 2 exons separated by 3 kb of intervening sequence. Multiple Kv3.3-hybridizing transcripts were found in mouse brain, liver, thymus, and heart.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Potassium Voltage Gated Channel Shaw Related Subfamily, Member 3 (KCNC3) | ELISA Kit Customized Service Offer |
- "Kv3.3 potassium channels in lens epithelium and corneal endothelium."Exp. Eye Res. 70:339-348(2000) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental nervous system phenotypes."Nat. Genet. 38:447-451(2006) [PubMed] [Europe PMC] [Abstract]