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Sal Like Protein 1 (SALL1)

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HSAL1; TBS; ZNF794; SAL1; Spalt-like transcription factor 1; Zinc finger protein 794; Zinc finger protein Spalt-1

Sal Like Protein 1 (SALL1)
CCC L021
HGNC 10524
MGI 1889585
PubMed 9425907
RGD 1309916
UniProt Q9NSC2
Wiki SALL1
SALL1 acted as a strong transcriptional repressor which could not be relieved by the addition of the histone deacetylase inhibitor trichostatin A. Using a yeast 2-hybrid screen, PIN2, an isoform of telomere repeat-binding factor 1 (TERF1), was identified as an interaction partner of SALL1. The interaction was confirmed in vitro in a GST pull-down assay. The authors proposed an involvement of SALL1 in the regulation of higher order chromatin structures and hypothesized that the protein may be a component of a distinct heterochromatin-dependent silencing process.SALL1 gene is expressed in a subset of human tissues, with highest expression in kidney, brain, and liver. SALL1 and SALL2 are expressed in different areas of the fetal brain, probably in distinct sets of neurons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sal Like Protein 1 (SALL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sal Like Protein 1 (SALL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sal Like Protein 1 (SALL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sal Like Protein 1 (SALL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sal Like Protein 1 (SALL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sal Like Protein 1 (SALL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sal Like Protein 1 (SALL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sal Like Protein 1 (SALL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sal Like Protein 1 (SALL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sal Like Protein 1 (SALL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sal Like Protein 1 (SALL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sal Like Protein 1 (SALL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sal Like Protein 1 (SALL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sal Like Protein 1 (SALL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sal Like Protein 1 (SALL1) ELISA Kit Customized Service Offer
  1. "Molecular analysis of SALL1 mutations in Townes-Brocks syndrome." Am. J. Hum. Genet. 64:435-445(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Townes-Brocks syndrome: detection of a SALL1 mutation hot spot and evidence for a position effect in one patient."Hum. Mutat. 14:377-386(1999) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt."Genomics 38:291-298(1996) [PubMed] [Europe PMC] [Abstract]
  6. "Mutations in the SALL1 putative transcription factor gene cause Townes-Brocks syndrome."Nat. Genet. 18:81-83(1998) [PubMed] [Europe PMC] [Abstract]
  7. "Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations." Nat. Genet. 40:287-289(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A SALL1 mutation causes a branchio-oto-renal syndrome-like phenotype."J. Med. Genet. 37:458-460(2000) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]