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Zinc Finger, BED-Type Containing Protein 1 (ZBED1)

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TRAMP; ALTE; DREF; Ac-Like Transposable Element

Zinc Finger, BED-Type Containing Protein 1 (ZBED1)
CCC L010
HGNC 447
PubMed 9887332
UniProt O96006
Wiki ZBED1
ZBED1 as a pseudoautosomal gene with a functional homolog on the Y chromosome. By PCR of teratocarcinoma cell line cDNA libraries, they obtained a full-length TRAMP cDNA. The putative 694-amino acid TRAMP protein shares sequence similarity with transposases of the Ac family.
Moreover, TRAMP shares similarity with Drosophila Dref, a transcriptional regulatory factor that specifically binds the promoter-activating element DNA replication-related element (DRE) of DNA replication-related genes. Northern blot analysis detected a 5-kb TRAMP transcript in all human tissues examined, with highest levels in skeletal muscle and heart. RT-PCR confirmed that TRAMP escapes X inactivation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, BED-Type Containing Protein 1 (ZBED1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, BED-Type Containing Protein 1 (ZBED1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, BED-Type Containing Protein 1 (ZBED1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, BED-Type Containing Protein 1 (ZBED1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, BED-Type Containing Protein 1 (ZBED1) ELISA Kit Customized Service Offer
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  2. "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification of a human homologue of the DREF transcription factor with a potential role in regulation of the histone H1 gene."J. Biol. Chem. 278:22928-22938(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Solution structure of the zinc finger BED domain of the zinc finger BED domain containing protein 1."Submitted (NOV-2005) to the PDB data bank