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Transmembrane Protein 49 (TMEM49)

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VMP1; TDC1; Vacuole membrane protein 1

Transmembrane Protein 49 (TMEM49)
CCC K483
HGNC 29559
MGI 1923159
PubMed 21712654
RGD 70367
UniProt Q96GC9
Wiki TMEM49
Tmem49 expression in the fetal pancreas at embryonic day 19, and expression remained elevated until postnatal day 11. Tmem49 mRNA levels decreased by postnatal day 23, and expression was not detectable after that time. Both 1.9- and 2.7-kb Tmem49 transcripts were detected at high levels in adult rat intestine, kidney, ovary, and placenta with moderate expression in liver, lung, stomach, thymus, brain, and testis, and weak expression in thyroid and retina. In situ hybridization of rat pancreas localized Tmem49 to acinar cells in acute pancreatitis tissue. Induction of Tmem49 was also observed in postischemic kidney in an experimental rat model. Subcellular fractionation and immunofluorescence microscopy localized Tmem49 to the Golgi apparatus and endoplasmic reticulum.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 49 (TMEM49) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 49 (TMEM49) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 49 (TMEM49) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 49 (TMEM49) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 49 (TMEM49) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 49 (TMEM49) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 49 (TMEM49) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 49 (TMEM49) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 49 (TMEM49) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 49 (TMEM49) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 49 (TMEM49) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 49 (TMEM49) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 49 (TMEM49) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 49 (TMEM49) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 49 (TMEM49) ELISA Kit Customized Service Offer
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  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Reduced expression of vacuole membrane protein 1 affects the invasion capacity of tumor cells."Oncogene 27:1320-1326(2008) [PubMed] [Europe PMC] [Abstract]
  6. "The TP53INP2 protein is required for autophagy in mammalian cells."Mol. Biol. Cell 20:870-881(2009) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]