PHD Finger Protein 11 (PHF11)
[Edit]NY-REN-34; BCAP; IGER; IgE Responsiveness,Atopic; BRCA1 C-terminus-associated protein; Renal carcinoma antigen NY-REN-34
Using autologous antibody, Scanlan et al. (1999) cloned PHF11, which they designated NY-REN-34, from a clear-cell renal carcinoma cDNA library. The deduced 191-amino acid protein contains a zinc finger motif. RT-PCR detected expression in all normal tissues tested, including lung, testis, small intestine, breast, liver, and placenta.Zhang et al. (2003) cloned PHF11 from a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E (IgE) levels and asthma.PCR analysis detected several splice variants, 1 of which was expressed in all tissues examined. A variant utilizing an alternative exon 1 was expressed in immune-related tissues and cells. Variants utilizing 2 alternative exons following exon 5, both of which contain premature stop codons, were detected only in lung and unactivated peripheral blood leukocytes, but not in activated cells.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant PHD Finger Protein 11 (PHF11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to PHD Finger Protein 11 (PHF11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to PHD Finger Protein 11 (PHF11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for PHD Finger Protein 11 (PHF11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for PHD Finger Protein 11 (PHF11) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant PHD Finger Protein 11 (PHF11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to PHD Finger Protein 11 (PHF11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to PHD Finger Protein 11 (PHF11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for PHD Finger Protein 11 (PHF11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for PHD Finger Protein 11 (PHF11) | ELISA Kit Customized Service Offer |
- "Antigens recognized by autologous antibody in patients with renal-cell carcinoma."Int. J. Cancer 83:456-464(1999) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma." Nat. Genet. 34:181-186(2003) [PubMed] [Europe PMC] [Abstract]
- "Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis."Genes Immun. 6:262-264(2005) [PubMed] [Europe PMC] [Abstract]
- "Functional characterization of the atopy-associated gene PHF11."J. Allergy Clin. Immunol. 121:1148-1154(2008) [PubMed] [Europe PMC] [Abstract]